PT-141
"Sexual Wellness Support"
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Product description
PT-141 (Bremelanotide) is a synthetic cyclic heptapeptide analogue of α-melanocyte-stimulating hormone (α-MSH), structurally derived from the Melanotan-II scaffold via removal of the C-terminal amide and formation of a lactam bridge between Asp⁵ and Lys¹⁰. It exhibits potent, non-selective agonist activity at melanocortin receptor subtypes — with highest affinity at MC4R — and has been extensively studied in preclinical models investigating the central melanocortin system. Its cyclic architecture confers enhanced metabolic stability relative to linear α-MSH analogues.
How to use it
Each vial arrives as lyophilized (freeze-dried) powder and must be reconstituted with bacteriostatic water before use in a research setting. Add the water slowly down the inside wall of the vial, then swirl gently until clear — never shake. Once reconstituted, keep it refrigerated and use within 28 days.
Open the step-by-step reconstitution guideStorage & stability
Sealed lyophilized vials are stable at ambient temperatures for 30 days and indefinitely at −20°C. After reconstitution, refrigerate at 2–8°C in the original vial and use within 28 days. Keep the vial out of direct light and avoid repeated temperature swings and agitation.
Quality & testing
Quality and purity tests are performed on random batches, covering identity (mass spec), purity (HPLC) and endotoxin results.
Browse our certificates of analysis →Shipping & returns
Orders placed before 3:00 PM ET on a business day are typically shipped the same day, in plain, discreet packaging; transit is estimated at 2–4 business days.
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About PT-141
In controlled laboratory environments, PT-141 is extensively studied for its role in melanocortin receptor activation and central nervous system signaling pathways. Researchers utilize this peptide to investigate how receptor-specific activation influences neurological responses and downstream endocrine effects. These mechanisms are essential for understanding how peptide signaling interacts with complex brain-centered regulatory systems.
Neuroendocrine and Behavioral Response Research
PT-141 is also explored in studies focused on neuroendocrine integration and behavioral signaling pathways. Laboratory models examine how this peptide may influence dopamine-related circuits, hormonal feedback loops, and neural response patterns. These insights are particularly relevant in research examining the relationship between neuropeptides and systemic hormonal activity.
Supplied in a premium lyophilized (freeze-dried) powder form, the 10mg format ensures optimal stability, precise measurement, and reliable reconstitution under strict laboratory conditions. It is well suited for dose-response studies and extended experimental protocols. Accurate peptide calculations during reconstitution help maintain consistent molarity across batches, ensuring reproducibility in in-vitro research models.
What distinguishes PT-141 in modern research is its selective interaction with melanocortin receptors, allowing researchers to investigate how targeted receptor activation influences neurological and endocrine pathways simultaneously. This provides deeper insight into how peptide signaling integrates with central regulatory systems and behavioral responses.
To preserve peptide integrity, strict cold-chain storage is recommended. Once reconstituted with bacteriostatic water, vials should be stored between 2°C and 8°C. Proper storage ensures stability and maintains biological activity throughout multi-phase research studies, supporting consistent and reliable data collection.
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FAQ
Common questions
Each vial contains lyophilized peptide, sealed under vacuum with a butyl stopper and aluminum crimp cap. Bacteriostatic water is sold separately.
Store the sealed vial at 2–8°C in a dark environment. After reconstitution, keep refrigerated and use within 28 days.
Yes — every batch ships with a signed COA showing HPLC purity, mass spec confirmation, and endotoxin results. Download the sample COA above.
Larger vials offer the same peptide at a lower per-mg cost. Reconstitution volume scales linearly with size.