Glutathione
" Cellular Antioxidant Support"
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Product description
Glutathione (GSH; L-Glutathione reduced; CAS# 70-18-8) is an endogenous tripeptide composed of γ-glutamate, cysteine, and glycine, characterised by an unusual γ-peptide bond between the glutamate side-chain carboxyl and the cysteine amine. It is the most abundant intracellular low-molecular-weight thiol and functions as the primary endogenous redox buffer in mammalian cells. GSH is studied as a biochemical research tool for investigating oxidative stress models, Nrf2/ARE pathway activation, glutathione peroxidase and reductase enzyme kinetics, and cellular redox homeostasis. Supplied by BIOSTACKS as a lyophilized powder for in vitro laboratory research use. This compound has not been authorized by Health Canada for any therapeutic, clinical, or human use.
How to use it
Each vial arrives as lyophilized (freeze-dried) powder and must be reconstituted with bacteriostatic water before use in a research setting. Add the water slowly down the inside wall of the vial, then swirl gently until clear — never shake. Once reconstituted, keep it refrigerated and use within 28 days.
Open the step-by-step reconstitution guideStorage & stability
Sealed lyophilized vials are stable at ambient temperatures for 30 days and indefinitely at −20°C. After reconstitution, refrigerate at 2–8°C in the original vial and use within 28 days. Keep the vial out of direct light and avoid repeated temperature swings and agitation.
Quality & testing
Quality and purity tests are performed on random batches, covering identity (mass spec), purity (HPLC) and endotoxin results.
Browse our certificates of analysis →Shipping & returns
Orders placed before 3:00 PM ET on a business day are typically shipped the same day, in plain, discreet packaging; transit is estimated at 2–4 business days.
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About Glutathione
In controlled laboratory environments, it is extensively studied for its role in neutralizing reactive oxygen species (ROS), maintaining redox homeostasis, and protecting cellular components from oxidative damage. Researchers utilize this compound to investigate how antioxidant systems support cellular integrity, particularly in models involving environmental stress, metabolic activity, and aging-related oxidative imbalance. These mechanisms are fundamental in studies related to anti-aging research pathways and cellular defense systems.
Detoxification and Cellular Protection Pathways
Glutathione plays a critical role in cellular detoxification processes, particularly within liver-associated models. Laboratory studies examine how it participates in phase II detoxification pathways, supporting the conjugation and elimination of metabolic byproducts and xenobiotics. These insights are essential in understanding how biological systems maintain internal balance and protect against toxic accumulation.
Supplied in a high-quality lyophilized (freeze-dried) powder form, the 1500mg format ensures maximum stability, precise measurement, and reliable reconstitution under proper laboratory conditions. This format is ideal for extended research protocols and high-volume experimental applications. Accurate calculations during reconstitution help maintain consistent concentrations across batches, ensuring reproducibility in in-vitro studies.
What distinguishes it in research is its central role in maintaining cellular redox equilibrium. Researchers investigate how it interacts with enzymatic systems, mitochondrial activity, and metabolic pathways to support overall cellular function. This makes it a key compound in studies focused on energy production, oxidative stress resilience, and long-term cellular performance.
To preserve compound integrity, strict cold-chain storage is recommended. Once reconstituted, Glutathione solutions should be stored between 2°C and 8°C and protected from light exposure to prevent degradation. Proper storage conditions ensure stability and maintain activity throughout multi-phase research studies.
FAQ
Common questions
Each vial contains lyophilized peptide, sealed under vacuum with a butyl stopper and aluminum crimp cap. Bacteriostatic water is sold separately.
Store the sealed vial at 2–8°C in a dark environment. After reconstitution, keep refrigerated and use within 28 days.
Yes — every batch ships with a signed COA showing HPLC purity, mass spec confirmation, and endotoxin results. Download the sample COA above.
Larger vials offer the same peptide at a lower per-mg cost. Reconstitution volume scales linearly with size.