MOTS-C
"Advanced Mitochondrial Regulation Peak Energy"
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Product description
MOTS-C (Mitochondrial Open reading frame of the twelve S rRNA-c, CAS# 1627580-64-6) is a 16-amino-acid mitochondria-derived peptide (MDP) encoded within the 12S rRNA gene of mitochondrial DNA — making it one of a small class of bioactive peptides with a mitochondrial rather than nuclear genomic origin. MOTS-C is studied in preclinical research for its role in mitochondria-to-nucleus retrograde signalling and its involvement in AMPK pathway activation, the folate cycle, de novo purine synthesis, and metabolic regulation models. Under cellular stress conditions, MOTS-C has been shown to translocate from mitochondria to the nucleus in vitro, where it interacts with nuclear gene regulatory elements. Supplied by BIOSTACKS as a lyophilized powder for in vitro laboratory research use. This compound has not been authorized by Health Canada for any therapeutic, clinical, or human use.
How to use it
Each vial arrives as lyophilized (freeze-dried) powder and must be reconstituted with bacteriostatic water before use in a research setting. Add the water slowly down the inside wall of the vial, then swirl gently until clear — never shake. Once reconstituted, keep it refrigerated and use within 28 days.
Open the step-by-step reconstitution guideStorage & stability
Sealed lyophilized vials are stable at ambient temperatures for 30 days and indefinitely at −20°C. After reconstitution, refrigerate at 2–8°C in the original vial and use within 28 days. Keep the vial out of direct light and avoid repeated temperature swings and agitation.
Quality & testing
Quality and purity tests are performed on random batches, covering identity (mass spec), purity (HPLC) and endotoxin results.
Browse our certificates of analysis →Shipping & returns
Orders placed before 3:00 PM ET on a business day are typically shipped the same day, in plain, discreet packaging; transit is estimated at 2–4 business days.
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About MOTS-C
In highly controlled laboratory environments, this peptide has been extensively studied for its fundamental role in regulating cellular energy balance, glucose utilization pathways, and complex metabolic adaptation mechanisms. A major focal point of modern scientific research involving the compound is its potent interaction with AMP-activated protein kinase (AMPK) activation, oxidative metabolism pathways, and adaptive stress signaling. These well-documented characteristics make it an exceptionally valuable asset for advanced in-vitro studies specifically focused on aging biology, endurance and energy efficiency models, and overarching mitochondrial health research. Researchers can cross-reference these specific pathways using data from prominent biotechnology databases.
FAQ
Common questions
Each vial contains lyophilized peptide, sealed under vacuum with a butyl stopper and aluminum crimp cap. Bacteriostatic water is sold separately.
Store the sealed vial at 2–8°C in a dark environment. After reconstitution, keep refrigerated and use within 28 days.
Yes — every batch ships with a signed COA showing HPLC purity, mass spec confirmation, and endotoxin results. Download the sample COA above.
Larger vials offer the same peptide at a lower per-mg cost. Reconstitution volume scales linearly with size.